Sleep Support

Relax & Rest

Fall asleep faster and stay asleep longer to command a good night's sleep.* Subscribe & Save 25%

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Plantwise dual-capsule supplement capsules

Plantwise Relax and Rest helps calm your mind to sink into a restful sleep with balancing adaptogens, herbs, and amino acids so you can wake up to a revitalized morning.*

Designed by a scientific advisory board, led by a Board Certified Clinical Nutritionist, using scientifically-studied herbs and amino acids to support a calm mind and improve sleep quality, latency, and duration (for occasional sleeplessness).*

Rested      Revitalized      Ready



Plantwise dual-capsule supplement capsules

Ingredients that
actually work:

Adaptogens from regeneratively-grown, organic whole hemp phytocannabinoids (CBD, CBE, CBG +) feed the endocannabinoid system (a master regulator of the body’s sleep-wake cycle).*

PharmaGABA® helps quiet a busy mind by reducing anxiousness and setting a calm mood.*

Venetron® Rafuma leaf improves GABA’s ability to bind to receptors in the brain and prevents the breakdown of serotonin (which modulates sleep and is a precursor of melatonin).*

5-HTP (works with GABA) helps reduce the time it takes to fall asleep, increases sleep duration, and improves sleep quality.*

Valerian shortens sleep latency, while Passionflower, Chamomile, and Lemon Balm work together to relax the mind and body.*

Melatonin binds to receptors in the brain and helps with the timing of your circadian rhythm, signaling it’s time for rest.*

Plantwise dual-capsule supplement capsules

Reviews (12)

Write a Review
  • 5
    Relax & Rest product

    Posted by J Robert Williams on Jun 4th, 2022

    I use the pillow app w my iPhone/iwatch and have used it consistently for 18 months, so I have some good baseline data. Since I started using Relax & Rest, both my sleep quality and sleep duration are both in an uptrend with sleep quality way up over my averages, and I’ll report back after I have a full month. Definitely off to a good start and feels great to string together multiple good nights of sleep in a row.

  • 5
    Woke up feeling refreshed

    Posted by Petie S. on May 30th, 2022

    Over the years I have tried many sleep aids. Some natural and some pharmaceuticals. Each of these products have left me feeling a bit foggy in the morning and as if I didn’t get my required REM or Deep sleep. After trying Relax and Rest, I have woken up refreshed and energized! It also has significantly decreased the length of time it takes me to fall asleep. I wear an Whoop bracelet most nights and my HRV has increased every night I have used the product (an increase in HRV is a great thing FYI!). Can’t recommend enough. Bravo.

  • 5
    I slept great!

    Posted by Pat B on May 27th, 2022

    This worked great for me. When I get busy my brain is still thinking of everything from the day and this helped chill that out and I had a great sleep.

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Suggested Use

Adults take 2 capsules once per day with food as needed, or as recommended by your healthcare practitioner.


Use only if the seal is intact. If any adverse reactions occur, immediately stop using this product and consult your doctor. If you have a medical condition, are taking medications (including anti-depressants or drugs with central nervous system or serotonergic activity), or are pregnant or nursing, consult with your healthcare practitioner before using this product. Melatonin may produce drowsiness. Do not drive, operate machinery or consume alcohol when taking this product. Not intended for use by persons under the age of 18. Keep out of reach of children.

Quality Assurance

Plantwise follows all cGMP manufacturing standards. Every Plantwise product undergoes third-party lab testing at two stages of the manufacturing process. First, each raw ingredient is tested against material specifications. Second, the finished product is quality tested to confirm it meets all label supplement fact panel claims. Plantwise dual-capsule products are free from GMOs and we source regeneratively farmed and organic ingredients whenever possible.

A deeper look inside the Plantwise Rest & Relax formula

  • Serving Size: 2 Capsules
  • Servings Per Contianer: 20
  • Vegan
  • Gluten-Free
  • Soy-Free
  • Non GMO


VOHO Panoramic Entourage™ Organic Hemp Whole Plant Extract

(standardized native spectrum phytocannabinoids 20 mg)

Amount Per Serving: 80 mg | + %DV

As seen on the oil side of the capsule, the whole hemp oil is clean CO2 extracted from regeneratively-grown, organic Futura 75, a European Union DNA-verified, heirloom industrial hemp cultivar. The whole hemp oil is Self-Affirmed GRAS and is independently tested for purity across 300 pesticides and herbicides and is solvent and isolate-free.

Phytocannabinoids, found naturally in hemp, support the most important physiological system that helps modulate all physiological systems in the body – the endocannabinoid system (ECS).*

The ECS influences sleep in multiple locations within the brain and plays a role in circadian components of sleep-wake cycling. Phytocannabinoids help support CB1 receptors (in the ECS) that trigger the release of sleep-inducing molecules, creating a calming effect and supporting REM sleep (our deepest phase of sleep).*

Venetron® Rafuma Leaf

a trademarked extract of the Rafuma leaf (Apocynum venetum)

Amount Per Serving: 50 mg | + %DV

Venetron Rafuma leaf extract has been shown to promote a positive outlook, alleviate occasional stress and improve sleep quality. The mechanism of action for these effects is thought to be related to preventing the breakdown of serotonin (which increases serotonin levels) throughout the day, resulting in increased production of melatonin at night. In addition, Venetron works along with the amino acid GABA and improves its ability to bind to receptors in the brain. By doing so, GABA helps quiet a busy mind, provide a calming effect, and alleviate stress that interferes with sleep.*

PharmaGABA® (gamma-aminobutyric acid)

Amount Per Serving: 100 mg | + %DV

GABA is an amino acid naturally produced in the brain that works by quieting an active, busy mind that can interfere with sleep. In doing so, GABA helps to reduce anxiousness and creates a calmness of mood that helps induce restful sleep. Therefore, supplemental GABA benefits sleep by aiding relaxation and providing relief from anxiety and stress that are known to cause occasional sleeplessness. PharmaGABA® is a natural form of GABA produced with the help of the probiotic Lactobacillus hilgardii – a beneficial lactic acid bacteria.*

5-Hydroxytryptophan (5-HTP)

(from Garcinia simplicifolia seed extract)

Amount Per Serving: 150 mg | + %DV

5-HTP is an amino acid derivative produced from tryptophan, which gets converted to serotonin. Serotonin helps regulate mood and anxiety and has a positive effect on sleep. 5-HTP has been shown to shorten the time to get to sleep and provides for a deeper sleep. In addition, 5-HTP increases serotonin which can be converted to melatonin – the important sleep regulating hormone. When 5-HTP is combined with GABA, the combination supports sleep duration and quality, while helping reduce sleep latency.*

Valerian (Valeriana officinalis) root extract

(standardized 0.80% valerenic acids 80 mcg)

Amount Per Serving: 100 mg | + %DV

Valerian root extract helps create a relaxing and sleep-supporting effect without inducing unwanted morning grogginess. Components of valerian inhibit the breakdown of GABA in the brain and induce calming relaxation. Additionally, valerian root extract helps reduce sleep latency while supporting sleep quality.*

Passionflower (Passiflora incarnata) flower extract

(8:1, plant equivalent 500 mg)

Amount Per Serving: 63 mg | + %DV

Chamomile (Matricaria recutita) flower extract

(10:1, plant equivalent 500 mg)

Amount Per Serving: 50 mg | + %DV

Lemon Balm (Melissa officinalis) leaf extract

(8:1, plant equivalent 500 mg)

Amount Per Serving: 63 mg | + %DV

These three well-known herbal extracts have a long history of use and help relax the body, calm the mind, and help prepare you for a restful sleep.*


(standardized 10% Anthocyanins 20 mg)

Amount Per Serving: 2 mg | + %DV

Melatonin is a hormone that the brain produces that helps with the timing of your circadian rhythm and sleep. Melatonin binds to receptors in the brain to reduce activity and levels of dopamine that help you stay awake. Your body produces melatonin naturally and, as melatonin levels rise in the evening, they let the body know it is nighttime and time for sleep. Numerous scientific and clinical studies have been published which establish melatonin supplementation’s usefulness in significantly reducing both sleep issues and length of time to get to sleep.*

+ Daily Value Not Established

Other ingredients: Organic Hemp Seed Oil, Vegetable Capsule (Hydroxypropyl Methylcellulose), Rice Hulls, Rice Extract Blend (Rice Extract, Rice Hulls, Gum Arabic, Sunflower Oil).

30-Day Plantwise Promise

Every body is different, which is why we offer 30 days to try Plantwise. If you’re not satisfied, simply return it for a refund, no questions asked.

Easy to Recycle Packaging

Our bottles and boxes are 100% recyclable curbside. Our dual-capsule bottle labels are easy to remove and the entire bottle can be recycled or reused.

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