Sleep Support

Relax & Rest

Fall asleep faster and stay asleep longer to command a good night's sleep.* Subscribe & Save 25%

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Plantwise dual-capsule supplement capsules

Plantwise Relax and Rest helps calm your mind to sink into a restful sleep with balancing adaptogens, herbs, and amino acids so you can wake up to a revitalized morning.*

Designed by a scientific advisory board, led by a Board Certified Clinical Nutritionist, using scientifically-studied herbs and amino acids to support a calm mind and improve sleep quality, latency, and duration (for occasional sleeplessness).*

Rested      Revitalized      Ready



Plantwise dual-capsule supplement capsules

Ingredients that
actually work:

Adaptogens from regeneratively-grown, organic whole hemp phytocannabinoids (CBD, CBE, CBG +) feed the endocannabinoid system (a master regulator of the body’s sleep-wake cycle).*

PharmaGABA® helps quiet a busy mind by reducing anxiousness and setting a calm mood.*

Venetron® Rafuma leaf improves GABA’s ability to bind to receptors in the brain and prevents the breakdown of serotonin (which modulates sleep and is a precursor of melatonin).*

5-HTP (works with GABA) helps reduce the time it takes to fall asleep, increases sleep duration, and improves sleep quality.*

Valerian shortens sleep latency, while Passionflower, Chamomile, and Lemon Balm work together to relax the mind and body.*

Melatonin binds to receptors in the brain and helps with the timing of your circadian rhythm, signaling it’s time for rest.*

Plantwise dual-capsule supplement capsules

Reviews (12)

Write a Review
  • 5
    Sleep Quality

    Posted by Don Fields on Jun 5th, 2023

    I have tried everything, and pursued sleep quality for years to improve performance. I eat well, I don't drink much, but sleep is my challenge in feeling my best for training and game day. This is my newfound upgrade, and my sleep tracker confirms.

  • 5
    REM SLEEP ! Found Here.

    Posted by Sam D on Jan 17th, 2023

    I had forgotten how wonderful REM sleep is, having restless sleep for longer than I care to admit. A close friend recommended "Relax & Rest" and now I am sleeping like a kid again. I feel so much better, and as result I am more productive at work, and actually rested enough to enjoy my free time. Highest Recommendation!

  • 5
    Finally! Sleeping through the night. . .

    Posted by Bernadette B on Nov 16th, 2022

    This is the first Plantwise product I tried (I've since tried their Pain Support and Immune Prime and love both!) and I am so excited--I haven't slept soundly through the night in probably 20 years; I can usually fall asleep fine, but I wake in the wee hours (2am, 3am, or 4am) and have a lot of trouble falling back asleep--my mind races. . . I began taking Relax & Rest (I take just one capsule) and I am amazed--even when I wake up in the middle of the night to go to the bathroom, I fall right back to sleep--no more middle-of-the-night anxiety-fueled tossing and turning. Thank you Relax & Rest! My whole day is better because I can finally sleep. . .

  • 5
    Awesome for sleep!

    Posted by Jasmine on Nov 9th, 2022

    I’m a self-described insomniac and these help me fall asleep about half an hour after taking them every time. They don’t make me groggy in the morning either. I love this and am about to order again!

  • 5
    If you want great sleep, buy this stuff immediately!

    Posted by Brad J on Aug 5th, 2022

    These are a sleep miracle for me. It usually takes me an hour plus to fall asleep (unless I over compensate with too much booze and pay for it in the morning!). I've been taking these for under a week and wow do they help me crash quickly. I'm not one who remembers my dreams, but I have been since taking these (which tell me I'm in a dead great sleep). Before taking Relax & Rest, I'd often wake up once or twice during the night. The past week, I have crashed quickly and slept soundly until my alarm goes off 8+ hours later. I haven't been sluggish when that alarm goes off and I can only attribute it to Relax & Rest. I am hooked! Highly recommend.

  • 5
    Best Sleep Ever!!!

    Posted by Gordon Froeb on Jul 26th, 2022

    I have tried a bunch of different sleep remedies and this is by far the best natural remedy ever. I wake up refreshed and feeling great. No more tossing and turning during the night or waking up in the middle of the night and then your mind starts spinning thinking about everything you need to do. It’s a solid 8 hours of sleep without interruption.

  • 5
    Wake up sunny and refreshed

    Posted by Steven Bava on Jun 29th, 2022

    All other supplements I've tried leave me groggy and or just 'off' when I wake up and I'm not a morning person. This product however not only lulls me to sleep so easily but I wake up ready and excited for the day. No more laying around for 30 minutes trying to get my bearings together.

  • 5
    Best Sleep Ever

    Posted by Richard Niemi on Jun 22nd, 2022

    I received my order of Relax & Rest two days ago and have taken it the past two nights. I can honestly say it is has been the best two nights of sleep I have had in a very long time. Every night I struggle with keeping my mind from racing about what tasks I have the next day or what I may have missed that previous day. Both of these worries keep me up until I’m exhausted, but not with Relax & Rest. The best part is that not like other sleep supplements, I DO NOT wake up groggy in tired. In fact, I wake up before my alarm ready to tackle the day.

  • 5
    Yes! Deep and REM are attainable!!

    Posted by Rick O on Jun 14th, 2022

    Getting to sleep has been easier since I began using. According to my fit bit stats I have gotten increasingly more deep and REM sleep over the past several nights as well. You know how much better you feel when you finally get some quality sleep. Highly recommend you try this product!

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Suggested Use

Adults take 2 capsules once per day with food as needed, or as recommended by your healthcare practitioner.


Use only if the seal is intact. If any adverse reactions occur, immediately stop using this product and consult your doctor. If you have a medical condition, are taking medications (including anti-depressants or drugs with central nervous system or serotonergic activity), or are pregnant or nursing, consult with your healthcare practitioner before using this product. Melatonin may produce drowsiness. Do not drive, operate machinery or consume alcohol when taking this product. Not intended for use by persons under the age of 18. Keep out of reach of children.

Quality Assurance

Plantwise follows all cGMP manufacturing standards. Every Plantwise product undergoes third-party lab testing at two stages of the manufacturing process. First, each raw ingredient is tested against material specifications. Second, the finished product is quality tested to confirm it meets all label supplement fact panel claims. Plantwise dual-capsule products are free from GMOs and we source regeneratively farmed and organic ingredients whenever possible.

A deeper look inside the Plantwise Rest & Relax formula

  • Serving Size: 2 Capsules
  • Servings Per Contianer: 20
  • Vegan
  • Gluten-Free
  • Soy-Free
  • Non GMO


VOHO Panoramic Entourage™ Organic Hemp Whole Plant Extract

(standardized native spectrum phytocannabinoids 20 mg)

Amount Per Serving: 80 mg | + %DV

As seen on the oil side of the capsule, the whole hemp oil is clean CO2 extracted from regeneratively-grown, organic Futura 75, a European Union DNA-verified, heirloom industrial hemp cultivar. The whole hemp oil is Self-Affirmed GRAS and is independently tested for purity across 300 pesticides and herbicides and is solvent and isolate-free.

Phytocannabinoids, found naturally in hemp, support the most important physiological system that helps modulate all physiological systems in the body – the endocannabinoid system (ECS).*

The ECS influences sleep in multiple locations within the brain and plays a role in circadian components of sleep-wake cycling. Phytocannabinoids help support CB1 receptors (in the ECS) that trigger the release of sleep-inducing molecules, creating a calming effect and supporting REM sleep (our deepest phase of sleep).*

Venetron® Rafuma Leaf

a trademarked extract of the Rafuma leaf (Apocynum venetum)

Amount Per Serving: 50 mg | + %DV

Venetron Rafuma leaf extract has been shown to promote a positive outlook, alleviate occasional stress and improve sleep quality. The mechanism of action for these effects is thought to be related to preventing the breakdown of serotonin (which increases serotonin levels) throughout the day, resulting in increased production of melatonin at night. In addition, Venetron works along with the amino acid GABA and improves its ability to bind to receptors in the brain. By doing so, GABA helps quiet a busy mind, provide a calming effect, and alleviate stress that interferes with sleep.*

PharmaGABA® (gamma-aminobutyric acid)

Amount Per Serving: 100 mg | + %DV

GABA is an amino acid naturally produced in the brain that works by quieting an active, busy mind that can interfere with sleep. In doing so, GABA helps to reduce anxiousness and creates a calmness of mood that helps induce restful sleep. Therefore, supplemental GABA benefits sleep by aiding relaxation and providing relief from anxiety and stress that are known to cause occasional sleeplessness. PharmaGABA® is a natural form of GABA produced with the help of the probiotic Lactobacillus hilgardii – a beneficial lactic acid bacteria.*

5-Hydroxytryptophan (5-HTP)

(from Garcinia simplicifolia seed extract)

Amount Per Serving: 150 mg | + %DV

5-HTP is an amino acid derivative produced from tryptophan, which gets converted to serotonin. Serotonin helps regulate mood and anxiety and has a positive effect on sleep. 5-HTP has been shown to shorten the time to get to sleep and provides for a deeper sleep. In addition, 5-HTP increases serotonin which can be converted to melatonin – the important sleep regulating hormone. When 5-HTP is combined with GABA, the combination supports sleep duration and quality, while helping reduce sleep latency.*

Valerian (Valeriana officinalis) root extract

(standardized 0.80% valerenic acids 80 mcg)

Amount Per Serving: 100 mg | + %DV

Valerian root extract helps create a relaxing and sleep-supporting effect without inducing unwanted morning grogginess. Components of valerian inhibit the breakdown of GABA in the brain and induce calming relaxation. Additionally, valerian root extract helps reduce sleep latency while supporting sleep quality.*

Passionflower (Passiflora incarnata) flower extract

(8:1, plant equivalent 500 mg)

Amount Per Serving: 63 mg | + %DV

Chamomile (Matricaria recutita) flower extract

(10:1, plant equivalent 500 mg)

Amount Per Serving: 50 mg | + %DV

Lemon Balm (Melissa officinalis) leaf extract

(8:1, plant equivalent 500 mg)

Amount Per Serving: 63 mg | + %DV

These three well-known herbal extracts have a long history of use and help relax the body, calm the mind, and help prepare you for a restful sleep.*


(standardized 10% Anthocyanins 20 mg)

Amount Per Serving: 2 mg | + %DV

Melatonin is a hormone that the brain produces that helps with the timing of your circadian rhythm and sleep. Melatonin binds to receptors in the brain to reduce activity and levels of dopamine that help you stay awake. Your body produces melatonin naturally and, as melatonin levels rise in the evening, they let the body know it is nighttime and time for sleep. Numerous scientific and clinical studies have been published which establish melatonin supplementation’s usefulness in significantly reducing both sleep issues and length of time to get to sleep.*

+ Daily Value Not Established

Other ingredients: Organic Hemp Seed Oil, Vegetable Capsule (Hydroxypropyl Methylcellulose), Rice Hulls, Rice Extract Blend (Rice Extract, Rice Hulls, Gum Arabic, Sunflower Oil).

30-Day Plantwise Promise

Every body is different, which is why we offer 30 days to try Plantwise. If you’re not satisfied, simply return it for a refund, no questions asked.

Easy to Recycle Packaging

Our bottles and boxes are 100% recyclable curbside. Our dual-capsule bottle labels are easy to remove and the entire bottle can be recycled or reused.

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